Vitamin D reduced fractures in older adults
Doctors in this analysis reviewed 11 separate bone-fracture studies covering more than 31,000 adults aged at least 65, who took varying doses of vitamin D or a placebo. The range for vitamin D was up to 2,000 IU per day. Compared to placebo, across all 11 studies, men and women who got the most vitamin D were 30 percent less likely to have a bone fracture of any kind, including hip, wrist and forearm.
Doctors said that the benefit began at 800 IU of vitamin D per day, and continued through the upper level of 2,000 IU per day. The U.S. recently increased its recommended dietary allowance to 600 IU of vitamin D per day for most people, and to 800 IU per day for those 70 and older.
Antioxidants reduce inflammation after fracture
After a hip fracture, chronic inflammation can slow recovery, doctors said. Vitamin E and carotenoids are two antioxidants with profound anti-inflammatory effects according to the doctors, who wanted to test for a link between antioxidant levels and chronic inflammation after a fracture.
Researchers measured blood levels of vitamin E, carotenoids, and signs of chronic inflammation in 148 people, immediately after a hip fracture, and at two, six, and 12 months later.
Those with the highest concentrations of alpha-tocopherol vitamin E and total circulating carotenoids had the lowest levels of inflammation. Doctors said that good levels of antioxidants may speed the average recovery time after a fracture, improve quality of life and help people regain mobility and maintain their independence.
Reference: New England Journal of Medicine; 2012, Vol. 367, No. 1, 40-9
From the October 2012 newsletter
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