Van's Health Foods

According to earlier studies, depression may have a link to cells damaged by oxidative stress. In this analysis, doctors compared antioxidant levels to signs of depression in 1,798 adults aged 20 to 85 and found, compared to those with lowest levels, people with the highest circulating levels of antioxidant carotenoids were 59 percent less likely to have depressive symptoms. There was also a direct link: as carotenoid levels increased, signs of depression decreased.

Carotenoids-the naturally occurring bright red, yellow, and orange pigments in fruits and vegetables like carrots-are powerful antioxidants. Doctors found three carotenoids in particular were most closely linked to better mood; beta-carotene in both men and women, and lutein and zeaxanthin in women only. Lutein and zeaxanthin also protect eyesight, as many earlier studies have confirmed. Discussing their findings, doctors said antioxidants may help reduce oxidative damage in the brain and hope new studies reveal more mood benefits of antioxidants.

Reference: British Journal of Nutrition; August, 2012, Electronic Prepublication

From the February 2013 newsletter

Vitamin D reduced fractures in older adults

Doctors in this analysis reviewed 11 separate bone-fracture studies covering more than 31,000 adults aged at least 65, who took varying doses of vitamin D or a placebo. The range for vitamin D was up to 2,000 IU per day. Compared to placebo, across all 11 studies, men and women who got the most vitamin D were 30 percent less likely to have a bone fracture of any kind, including hip, wrist and forearm.

Doctors said that the benefit began at 800 IU of vitamin D per day, and continued through the upper level of 2,000 IU per day. The U.S. recently increased its recommended dietary allowance to 600 IU of vitamin D per day for most people, and to 800 IU per day for those 70 and older.

Antioxidants reduce inflammation after fracture

After a hip fracture, chronic inflammation can slow recovery, doctors said. Vitamin E and carotenoids are two antioxidants with profound anti-inflammatory effects according to the doctors, who wanted to test for a link between antioxidant levels and chronic inflammation after a fracture.

Researchers measured blood levels of vitamin E, carotenoids, and signs of chronic inflammation in 148 people, immediately after a hip fracture, and at two, six, and 12 months later.

Those with the highest concentrations of alpha-tocopherol vitamin E and total circulating carotenoids had the lowest levels of inflammation. Doctors said that good levels of antioxidants may speed the average recovery time after a fracture, improve quality of life and help people regain mobility and maintain their independence.

Reference: New England Journal of Medicine; 2012, Vol. 367, No. 1, 40-9

From the October 2012 newsletter